Medium dependant production of corymbiferone a novel product from Penicillium hordei cultured on plant tissue agar

Medium dependant production and the structure elucidation of corymbiferone (1) from the fungus Penicillium hordei grown on oatmeal and macerated tulip, yellow onion and red onion agars are reported. Compound 1 possesses an unusual oxygenated aromatic structure with a lactone bridge preventing full aromatization of the molecule, resulting in several unusual chemical shifts.