Synthesis of azide-alkyne fragments for 'click' chemical applications; formation of oligomers from orthogonally protected trialkylsilyl-propargyl azides and propargyl alcohols

A copper catalyst was used in [3+2] cycloadditions of propargyl alcohols and trialkylsilyl azides. The triazole cycloadducts can be iteratively extended in either direction to prepare higher order oligomers.