A new one-step synthesis of stable 3-aryl-trans-5,6-dihydroxy-5,6-dihydro-1,2,4-oxadiazines

An easy and simple synthesis of 3-aryl-trans-5,6-dihydroxy-5,6-dihydro-1,2,4-oxadiazines 4a-e from arylamidoximes 1a-e and glyoxal 2 is described.