کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5372098 1503978 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of steroid hormone progesterone on the properties of phosphatidyl serine monolayers and thin liquid films
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
Influence of steroid hormone progesterone on the properties of phosphatidyl serine monolayers and thin liquid films
چکیده انگلیسی

In this work the capability of Progesterone (Prog) to penetrate to phosphatidyl serine (PS) monolayers (detected by equilibrium and dynamic surface tensions) and to induce rupture of PS thin liquid films (TLFs, known as foam films) in presence of Ca2+ ions is studied. TLF studies reveal that the presence of Ca2+ ions changes the type of PS films from thicker common black films to bilayer Newton black films and that the addition of Prog results in film destabilization and rupture. The effects of Prog in presence of Ca2+ ions were observed with the films consisting of negatively charged PS but not of neutral phospholipids. The results correlate with the proposed physiological role of Prog and Ca2+ in the acrosome reaction. The model of TLFs is used for the first time to study membrane fusion during acrosome reaction and proposes several new qualitative and quantitative parameters for studying of this reaction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biophysical Chemistry - Volume 130, Issues 1–2, October 2007, Pages 48-54
نویسندگان
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