کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5372214 | 1503981 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Arsenite interactions with phospholipid bilayers as molecular models for the human erythrocyte membrane
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کلمات کلیدی
DSCdMPCDPHdimyristoylphosphatidylcholineDMPEdimyristoylphosphatidylethanolamine1,6-diphenyl-1,3,5-hexatriene - 1،6-دیفنیل-1،3،5-هگزیدریلarsenite - آرسنیتArsenic - آرسنیکlarge unilamellar vesicles - بزرگ کیسه های بدون انعطاف پذیرFluorescence anisotropy - بی خوابی فلورسانسیPhospholipid bilayer - دو لایه فسفولیپیدErythrocyte membrane - غشای erythrocyteGeneral polarization - قطبش عمومیLUV - لوو
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Arsenite interactions with phospholipid bilayers as molecular models for the human erythrocyte membrane Arsenite interactions with phospholipid bilayers as molecular models for the human erythrocyte membrane](/preview/png/5372214.png)
چکیده انگلیسی
There are scanty reports concerning the effects of arsenic compounds on the structure and functions of cell membranes. With the aim to better understand the molecular mechanisms of the interaction of arsenite with cell membranes we have utilized bilayers of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE), representative of phospholipid classes located in the outer and inner monolayers of the human erythrocyte membrane, respectively. The capacity of arsenite to perturb the bilayer structures was determined by X-ray diffraction and fluorescence spectroscopy, whilst the modification of their thermotropic behaviour was followed by differential scanning calorimetry (DSC). The experiments carried out by X-ray diffraction and calorimetry clearly indicated that NaAsO2 interacted with DMPE and modified its thermotropic behaviour. No such information has been so far reported in the literature.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biophysical Chemistry - Volume 127, Issues 1â2, April 2007, Pages 28-35
Journal: Biophysical Chemistry - Volume 127, Issues 1â2, April 2007, Pages 28-35
نویسندگان
Mario Suwalsky, Cecilia Rivera, Fernando Villena, Carlos P. Sotomayor, Malgorzata Jemiola-Rzeminska, Kazimierz Strzalka,