Neutron scattering and HPLC study on l-ascorbic acid and its degradation

The present paper shows a systematic dynamic and kinetic study on l-ascorbic acid and its degradation at high temperature. The neutron scattering study allows, through the behavior of quasi-elastic neutron scattering (QENS) spectra, to characterize the diffusive dynamics of l-ascorbic acid in water mixtures. Ascorbic acid undergoes degradation process at high temperature, but the presence of trehalose in solution markedly avoids ascorbic acid loss enhancing its t1/2 (half life time), as determined by high performance liquid chromatography (HPLC).