Diffusion-weighted imaging with a rapid repeated hole-burning sequence

Diffusion-weighted imaging in the presence of extremely short T2-relaxation time is generally not feasible with a standard PGSE experiment due to the superposed signal decays caused primarily by T2-relaxation and secondarily by diffusion. Here, we present a new method for diffusion-weighted imaging achieved by a nearly T2-independent pre-experiment where a DANTE-pulse train is repeated rapidly.