Synthesis and characterization of siloxane sulfobetaine antimicrobial agents

► We had synthesized a novel kind of antibacterial agent siloxane sulfobetaine. ► The SSB contains quaternary ammonium and reactive siloxane groups. ► The antibacterial rate of SSB coated glass is higher than 99.96% within 24 h. ► The antibacterial rate of resultant surface is higher than 95.0% after washing. ► No skin stimulation and no toxicity to animal are found in the SSB.