Efficient synthesis of highly fluorescent carbon dots by microreactor method and their application in Fe3 + ion detection

- A rapid, continuous carbon dots synthesis technique was proposed by using a microreactor method.
- The CDs can be synthesized at a large scale in less than 5 min, and a high quantum yield of 60.1% was achieved.
- A powerful and portable tool for the rapid and efficient online synthesis of CDs was developed.
- The fluorescence probe shows high sensitivity and selectivity for Fe3 + detection.

Rapidly obtaining strong photoluminescence (PL) of carbon dots with high stability is crucial in all practical applications of carbon dots, such as cell imaging and biological detection. In this study, we proposed a rapid, continuous carbon dots synthesis technique by using a microreactor method. By taking advantage of the microreactor, we were able to rapidly synthesized CDs at a large scale in less than 5 min, and a high quantum yield of 60.1% was achieved. This method is faster and more efficient than most of the previously reported methods. To explore the relationship between the microreactor structure and CDs PL properties, Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) were carried out. The results show the surface functional groups and element contents influence the PL emission. Subsequent ion detection experiments indicated that CDs are very suitable for use as nanoprobes for Fe3 + ion detection, and the lowest detection limit for Fe3 + is 0.239 μM, which is superior to many other research studies. This rapid and simple synthesis method will not only aid the development of the quantum dots industrialization but also provide a powerful and portable tool for the rapid and continuous online synthesis of quantum dots supporting their application in cell imaging and safety detection.

Microreactor method is faster and more efficient than most of the previously reported methods synthesize carbon dots.207