Novel tetraphenylethylene diol amphiphile with aggregation-induced emission: self-assembly, cell imaging and tagging property

- First report of diol based tetraphenylethylene amphiphile with aggregation-induced emission property
- Self-assembly to form unique cubic superstructures
- Improved cellular uptake in comparison to controlled compound for bioimaging
- Better fluorescence tagging property after attachment with gold nanoparticles

In this study, we reported a novel tetraphenylethylene diol amphiphile (2) with aggregation-induced emission property which self-assembled to form unique 3D cubic superstructure. This TPE amphiphile with strong bluish green emission exhibited high biocompatibility and improved cellular uptake. Moreover, this highly fluorescent molecule was conjugated with gold nanoparticles and used as a fluorescent tagging agent. Altogether, results supported the cell-imaging and fluorescent tagging properties of tetraphenylethylene diol amphiphile.

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