کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5434354 | 1509141 | 2017 | 6 صفحه PDF | دانلود رایگان |

- Aggregation-induced emission fluorescent polymeric nanoparticles
- Microwave-assisted multicomponent reactions
- The experimental conditions of Kabachnik-Fields reaction are rather mild.
- The PEGMA-TPE FPNs possess excellent properties and promising for bioimaging applications.
The development of simple and effective methods for synthesis of fluorescent polymeric nanoparticles (FPNs) with aggregation-induced emission (AIE) plays an important role for the biomedical applications of AIE-active FPNs. In present work, we developed a facile strategy for the fabrication of AIE-active FPNs by a post-polymerization method based on the microwave-assisted Kabachnik-Fields (KF) reaction, which can conjugate with poly(PEGMA-NH2), AIE-active dye (TPE-CHO) and diethyl phosphate (DP) under microwave irradiation within 5Â min. The characterization results confirm that PEGMA-TPE FPNs are successfully prepared through the microwave-assisted KF reaction. The resultant AIE-active FPNs show high water dispersity, intensive fluorescence and low cytotoxicity. These features make these AIE-active FPNs great potential for biomedical applications. Moreover, the microwave-assisted KF reaction is simple, fast, atom economy that should be a general strategy for the fabrication of various multifunctional AIE-active FPNs. We believe this work will open up a new avenue for the preparation of AIE-active functional materials with great potential for different applications.
A novel microwave-assisted Kabachnik-Fields reaction was reported for the fabrication of fluorescent polymeric nanoparticles with aggregation-induced emission feature and utilized for biological imaging applications.121
Journal: Materials Science and Engineering: C - Volume 80, 1 November 2017, Pages 578-583