کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434354 1509141 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microwave-assisted multicomponent reactions for rapid synthesis of AIE-active fluorescent polymeric nanoparticles by post-polymerization method
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Microwave-assisted multicomponent reactions for rapid synthesis of AIE-active fluorescent polymeric nanoparticles by post-polymerization method
چکیده انگلیسی


- Aggregation-induced emission fluorescent polymeric nanoparticles
- Microwave-assisted multicomponent reactions
- The experimental conditions of Kabachnik-Fields reaction are rather mild.
- The PEGMA-TPE FPNs possess excellent properties and promising for bioimaging applications.

The development of simple and effective methods for synthesis of fluorescent polymeric nanoparticles (FPNs) with aggregation-induced emission (AIE) plays an important role for the biomedical applications of AIE-active FPNs. In present work, we developed a facile strategy for the fabrication of AIE-active FPNs by a post-polymerization method based on the microwave-assisted Kabachnik-Fields (KF) reaction, which can conjugate with poly(PEGMA-NH2), AIE-active dye (TPE-CHO) and diethyl phosphate (DP) under microwave irradiation within 5 min. The characterization results confirm that PEGMA-TPE FPNs are successfully prepared through the microwave-assisted KF reaction. The resultant AIE-active FPNs show high water dispersity, intensive fluorescence and low cytotoxicity. These features make these AIE-active FPNs great potential for biomedical applications. Moreover, the microwave-assisted KF reaction is simple, fast, atom economy that should be a general strategy for the fabrication of various multifunctional AIE-active FPNs. We believe this work will open up a new avenue for the preparation of AIE-active functional materials with great potential for different applications.

A novel microwave-assisted Kabachnik-Fields reaction was reported for the fabrication of fluorescent polymeric nanoparticles with aggregation-induced emission feature and utilized for biological imaging applications.121

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 80, 1 November 2017, Pages 578-583
نویسندگان
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