Green synthesis of copper (0) nanoparticles with cyanidine-O-3-glucoside and its strong antimicrobial activity

- A new method for nanoparticles at low temperature and short reaction time.
- The cyanidine-O-3-glucoside can reduce Cu(II) from CuCl2 to Cu (0), forming nanoparticles.
- The CuNPs showed strong inhibitory power on the growth of Gram (+) and Gram (−).

Cu nanoparticles (CuNPs) were biosynthesized by green nanotechnology and they showed a inhibitory power on the growth of Gram (+) and Gram (−). CuNPs synthesis (0) was performed at 65 °C from a solution of copper chloride and using as reducing cyanidine-O-3-glucoside, selectively obtained from the skin of red plum (Pronus domestic). Their characterization has shown typical UV-Vis bands, Cu nanoparticles refers to surface plasmon resonance (SPR) at 550 nm. Structural analysis by HRTEM evidence growth is in the (1 1 1) plane of the fcc phase of metallic Cu, with a size close to 10 nm, with a quasi-spherical morphology, due to the role as surfactant of the cyanidine-O-3-glucoside for the preparation of metal nanoparticles.

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