Open heavy-flavor measurements in ultra-relativistic nuclear collisions

Recent results from open heavy-flavor measurements in proton-proton (pp), proton/deuteron-nucleus (p/d-A), and nucleus-nucleus collisions (A-A) at RHIC and at the LHC are presented. Predictions from theoretical models are compared with the data, and implications for the properties of the hot and dense medium produced in ultra-relativistic heavy-ion collisions are discussed.