| کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
|---|---|---|---|---|
| 5501324 | 1534848 | 2017 | 4 صفحه PDF | دانلود رایگان |
کلمات کلیدی
1.مقدمه
2. دریافت آنتی اکسیدان ها و انجام ورزش های سبک به عنوان مداخلاتی در برابر پیری مغز:
2.1. دریافت یک مکمل آنتی اکسیدان به صورت تنها
2.2. ورزش
3. آیا ترکیب آنتی اکسیدان ها و ورزش، به فواید بیشتری منجر می‌شود؟
4. نتیجه گیری
- Single antioxidant supplementation (vitamins E and C) has limited effects on motor and cognitive function.
- Combination of antioxidants is more successful at reversing age-related declines in brain function.
- Exercise improves motor and cognitive function in rodents and humans.
- Controversial and limited outcomes of combining exercise and antioxidants require further research.
Age-related declines in motor and cognitive function have been associated with increases in oxidative stress. Accordingly, interventions capable of reducing the oxidative burden would be capable of preventing or reducing functional declines occurring during aging. Popular interventions such as antioxidant intake and moderate exercise are often recommended to attain healthy aging and have the capacity to alter redox burden. This review is intended to summarize the outcomes of antioxidant supplementation (more specifically of vitamins C and E) and exercise training on motor and cognitive declines during aging, and on measures of oxidative stress. Additionally, we will address whether co-implementation of these two types of interventions can potentially further their individual benefits. Together, these studies highlight the importance of using translationally-relevant parameters for interventions and to study their combined outcomes on healthy brain aging.
Journal: Experimental Gerontology - Volume 94, August 2017, Pages 69-72