کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5510077 1400481 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterization of serological neo-epitope biomarkers reflecting collagen remodeling in clinically stable chronic obstructive pulmonary disease
ترجمه فارسی عنوان
تشخیص زیستباکاریهای نئو اپیتوپ سرولوژیک بازسازی کلاژن در درمان بیماری مزمن انسدادی مزمن ریوی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
چکیده انگلیسی
Serological biomarkers of collagen remodeling were elevated in subjects with COPD as compared with healthy individuals. Biomarker levels were significantly correlated with measures of dyspnea, indicating a relationship with degree of symptoms, while only C6M showed a weak but significant association with lung function. Biomarker levels were not related to GOLD grades, which was in line with previous studies indicating that ECM remodeling may be related to disease activity rather than severity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Biochemistry - Volume 49, Issue 15, October 2016, Pages 1144-1151
نویسندگان
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