کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5511319 1539856 2017 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Germ cell neoplasia in situ: The precursor cell for invasive germ cell tumors of the testis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Germ cell neoplasia in situ: The precursor cell for invasive germ cell tumors of the testis
چکیده انگلیسی
Germ cell neoplasia in situ is the non-invasive precursor cell of origin for type II testicular germ cell tumors. It has long been postulated that germ cell neoplasia in situ is derived from defective germ cell development during embryonic life, and although it is impossible to trace in vivo the progression from fetal germ cell to germ cell neoplasia in situ to tumor, there is a large volume of evidence supporting this theory. Current studies focus on understanding how germ cell neoplasia in situ forms, how these cells are activated at puberty and how they transform to invasive tumors of various subtypes. Such information is informing novel diagnostic and therapeutic options.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The International Journal of Biochemistry & Cell Biology - Volume 86, May 2017, Pages 22-25
نویسندگان
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