کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5530880 | 1549441 | 2017 | 5 صفحه PDF | دانلود رایگان |
We report results from an acute, single case study in the pig liver on the effects of a tissue ablation protocol (we named cryoelectrolysis) in which 10Â min of cryosurgery, with a commercial cryosurgical probe, are delivered after 10Â min of electrolysis generated by a current of about 60Â mA. The histological appearance of tissue treated with cryoelectrolysis is compared with the appearance of tissue treated with 10Â min of cryosurgery alone and with 10Â min of electrolysis alone. Histology done after 3Â h survival shows that the mixed rim of live and dead cells found around the ablated lesion in both cryosurgery and electrolytic ablation is replaced by a sharp margin between life and dead cells in cryoelectrolysis. The appearance of the dead cells in each, cryoelectrolysis, cryosurgery and electrolytic ablation is different. Obviously, this is an acute study and the results are only relevant to the conditions of this study. There is no doubt that additional acute and chronic studies are needed to strengthen and expand the findings of this study.
Journal: Cryobiology - Volume 78, October 2017, Pages 110-114