Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in human

Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in human

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug Metabolism and Pharmacokinetics - Volume 32, Issue 5, October 2017, Pages 255-264

Jun Hosogi, Rui Ohashi, Hiroshi Maeda, Satoshi Tashiro, Eiichi Fuse, Yorihiro Yamamoto, Takashi Kuwabara,