کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5547337 | 1556045 | 2016 | 7 صفحه PDF | دانلود رایگان |
IntroductionTraditional Chinese medicine (TCM) plays an important role in the treatment of dyslipidemia and it is important to identify an objective index for the TCM syndrome. This study focused on exploring the correlation between TCM syndrome and the serum concentration of adiponectin (APN) and peroxynitrite (ONOOâ) in dyslipidemia patients.MethodsCross-sectional study design was used. Patients with dyslipidemia were assigned with corresponding TCM scores and their APN and ONOOâ serum content measured. We also explored the characteristics of APN and ONOOâ in different TCM syndromes and their relationship between patient's TCM scores.ResultsThe results indicated the serum levels of APN and ONOOâ were higher for those people with an Excess Syndrome than for those with a Deficiency Syndrome (P < 0.01). In Deficiency Syndrome, the clinical TCM scores showed negative correlation with and APN (r = â0.46, P < 0.01), and positive with ONOOâ (r = 0.58, P < 0.01). In Excess Syndrome, the TCM scores showed negative correlation with APN (r = â0.72, P < 0.01), and positive with ONOOâ (r = 0.50, P < 0.01).ConclusionsAs the serum levels of APN and ONOOâ appeared to be correlated with the TCM scores, these parameters could be potentially be used as objective and standardized biomarkers for TCM syndrome differentiation.
Journal: European Journal of Integrative Medicine - Volume 8, Issue 6, December 2016, Pages 973-979