Feature ArticleMultiple Myeloma: The Role of the Primary Care Nurse Practitioner

- Multiple myeloma is a progressive hematologic disease.
- Multiple myeloma is often diagnosed during a routine physical examination.
- Prompt recognition, early referral, and monitoring may extend patient survival.

Multiple myeloma is a hematologic disease characterized by an excessive number of abnormal plasma cells that infiltrate the bone marrow and overproduction of monoclonal immunoglobulins. It is the third most prevalent hematologic disease and makes up just over 15% of all hematologic malignancies. Patients may present with 1 or more nonspecific symptoms of hypercalcemia, renal insufficiency, anemia, or new-onset bone pain. Early recognition, referral, and monitoring may improve the quality of life and extend the survival of patients.