کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5580773 1404183 2016 29 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Management and Outcomes in Metaplastic Breast Cancer
ترجمه فارسی عنوان
مدیریت و نتایج سرطان پستان متاپلستیک
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی
Metaplastic breast cancer (MBC) constitutes a rare clinical entity with special clinicopathologic, immunohistochemical, and molecular features. Resistance to systemic therapies, whether chemotherapy or hormonal therapy, is among its main characteristics, which in turn explains the poor prognosis and renders its management a challenge. Thus, the scope of the present review is to discuss the current therapeutic strategies for MBC in clinical practice and the corresponding outcomes and to suggest possible directions for future research. Potential novel targeted therapies could provide a hope for better outcomes but limited data are available owing to the rarity of MBC. As knowledge accumulates on the pathogenesis and genetic characteristics of MBC, emphasis should be given to the implementation of more targeted treatments, which will allow more efficient and individualized management of the disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Breast Cancer - Volume 16, Issue 6, December 2016, Pages 437-443
نویسندگان
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