کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5584919 | 1568005 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Association of serum n-3 polyunsaturated fatty acids with psychological distress in the second and third trimesters of pregnancy: Adjunct Study of Japan Environment and Children's Study
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کلمات کلیدی
EPADPAPUFAsn-3 Polyunsaturated fatty acids - n-3 اسیدهای چرب اشباع نشدهEicosapentaenoic acid - اسید ایکوزاپنتانوئیکdocosapentaenoic acid - اسید داکوزاپنتانوئیکdocosahexaenoic acid - اسید داکوزاگزوائونیکPolyunsaturated fatty acids - اسید چرب اشباع نشدهPregnancy - بارداریDHA - دوکوساهگزائنوئیک اسیدconfidence interval - فاصله اطمینانCase-control study - مطالعه مورد شاهدیodds ratio - نسبت شانس هاPsychological distress - پریشانی روانی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوشیمی بالینی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The results of several epidemiological studies and clinical trials investigating the effects of n-3 polyunsaturated fatty acids (PUFAs) on antenatal and postnatal depression remain controversial. In a previous case-control study of early pregnancy in Japan, we found an inverse association between eicosapentaenoic acid and risk of psychological distress after adjusting for possible confounders. Here, in a 1:2 matched case-control study, we further investigated the possible relationship between serum n-3 PUFAs and risk of psychological distress in the second and third trimesters of pregnancy. The psychological distress group (n=71) consisted of subjects with a score of â¥13 on the Kessler Psychological Distress Scale. The control group (n=142) was matched for age, educational level, and family income. Fatty acid composition of total lipid was determined from serum samples by gas chromatography. Associations between fatty acid levels and incidence of psychological distress were evaluated by logistic regression. Sixty-six percent of blood samples were collected in the second trimester and the remainder in the third. There were no significant differences in any of the n-3 PUFAs between the two groups. After adjustment for possible confounders, none of the n-3 PUFAs showed an association with risk of psychological distress. Peripheral n-3 PUFA levels might not influence the risk of psychological distress in later pregnancy. Further research is warranted to clarify this finding.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) - Volume 114, November 2016, Pages 21-27
Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) - Volume 114, November 2016, Pages 21-27
نویسندگان
Kei Hamazaki, Akiko Harauma, Satoru Tanabe, Miho Namai, Toru Moriguchi, Hidekuni Inadera,