کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5587596 | 1568856 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Neuropeptide Y in the brain of Euphlyctis cyanophlyctis tadpoles responds to hypoxic stress
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
NASCRFNHDinfundibular recessdissolved oxygen - اکسیژن محلولcorticotrophin releasing factor - عامل آزاد کننده کورتیکوتروپینHypothalamo-pituitary-adrenal axis - محور هیپوتالامو-هیپوفیز-آدرنالHPA - میلی بار یا هکتوپاسکالnucleus accumbens septi - هسته accumbens septidorsal pallium - پالم پشتیMedial pallium - گوشته جانبی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Neuropeptide Y (NPY) has emerged as a novel peptide to antagonize various physiological consequences of stress within a mammalian brain. Hypoxia induced neuropeptide Y release in mammalian systems is well established. However, the possible role of NPY in regulating the effects of oxygen variation in lower vertebrates has not been investigated. We have studied the distribution and neuro-anatomical expression of NPY in the brain of Euphlyctis cyanophlyctis tadpoles, exposed to normal and reduced oxygen levels using immunohistochemistry. Animals exposed to hypoxia (<2Â mg/ml) exhibited a significant amplification of NPY-immunoreactivity throughout the brain. Increased NPY-ir perikarya appeared in all the sub-divisions of pallium, septum and preoptic area of telencephalon; suprachiasmatic nucleus, central and lateral thalamus, infundibulum and habenular regions of diencephalon; and nucleus cerebella and medulla of rhombencephalon. Most of these regions form the stress and anxiety regulating centers of a vertebrate brain and some of the parallel regions also respond to respiratory reflexes in mammals. Hence, our results suggest NPY induced modulation of hypoxia in Euphlyctis cyanophlyctis tadpoles.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General and Comparative Endocrinology - Volume 251, 15 September 2017, Pages 38-45
Journal: General and Comparative Endocrinology - Volume 251, 15 September 2017, Pages 38-45
نویسندگان
Ishfaq Ali, Shobha Bhargava,