کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5600296 | 1405294 | 2017 | 36 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Rapid Eye Movement Sleep Behavior Disorder
ترجمه فارسی عنوان
اختلال خواب در حرکت سریع چشم
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کلمات کلیدی
RBDRSWAiRBDDLBREMDEBMSAsld - SldMultiple system atrophy - آتروفی سیستم چندگانهRapid eye movement sleep behavior disorder - اختلال رفتار خواب حرکت سریع چشمmild cognitive impairment - اختلال شناختی خفیفParkinson disease - بیماری پارکینسونDementia with Lewy bodies - تهوع و استفراغ با بدن LewyNeurodegeneration - تولید نوروژنیکrapid eye movement - حرکت سریع چشمAlzheimer’s dementia - زوال آلزایمرMCI - همراه اولPSG - پاری سن ژرمنPolysomnography - پلی سومنوگرافی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by abnormal behaviors emerging during REM sleep that may cause injury or sleep disruption. The diagnosis requires polysomnography (PSG) demonstrating a loss of normal skeletal muscle atonia during REM sleep. RBD results from dysfunction of the brain stem circuits responsible for maintaining normal REM sleep atonia and suppressing behaviors during REM sleep. The diagnosis of idiopathic RBD (IRBD), that is, RBD without an identifiable cause, is frequently followed years later by the development of a neurodegenerative disorder, most commonly one of the synucleinopathies. As such, RBD is often a step in the progression of a neurodegenerative disorder. In this circumstance, it is a manifestation of neurodegeneration occurring in the brain stem before spreading to adjacent and other CNS regions, resulting in the development of symptoms and signs that permit recognition of a specific neurodegenerative disorder. RBD has been linked with narcolepsy and has been associated with a variety of other disorders. The management of RBD focuses on preventive/safety measures, counseling, monitoring for the development of a neurodegenerative disorder, and pharmacotherapy, which is typically effective but not well understood. The purpose of this article is to review and update our current understanding of the clinical features, epidemiology, demographics, pathophysiology, evaluation, diagnosis, differential diagnosis, causes, associations, and the clinical management of RBD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chest - Volume 152, Issue 3, September 2017, Pages 650-662
Journal: Chest - Volume 152, Issue 3, September 2017, Pages 650-662
نویسندگان
Carlos L. MD, Nattapong MD, FCCP, Kumar MD,