کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5654517 1407282 2017 26 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interferon-free antiviral therapy for chronic hepatitis C among patients in the liver transplant setting
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Interferon-free antiviral therapy for chronic hepatitis C among patients in the liver transplant setting
چکیده انگلیسی
Chronic hepatitis C (HCV) infection remains a major public health problem with many infected individuals worldwide. The revolutionary discovery of highly effective direct-acting antivirals (DAAs) makes chronic HCV infection a curable disease, even in patients with advanced liver disease. Liver function may improve shortly after initiation of antiviral therapy in patients on the waiting list and could even obviate the need for transplantation. However, whether these short term benefits also result in a favorable prognosis on the long-term remains to be seen and this fuels the discussion whether DAAs should be used prior to liver transplantation in all patients. Following liver transplantation, DAA treatment is also highly effective so that postponing antiviral treatment to the post-transplant setting may be better for certain patients. Furthermore, the discussion whether HCV positive organ donors should be used now viral eradication is achieved in almost all patients has regained interest.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Gastroenterology - Volume 31, Issue 2, April 2017, Pages 219-225
نویسندگان
, , , , , , ,