Campylobacter bacteremia in London: A 44-year single-center study

PurposeCampylobacter species are a well-recognized but rare cause of bloodstream infection.MethodsHere we reviewed 41 cases of Campylobacter bloodstream infection occurring at a single center in London over 44 years, comprising 0.2% of all recorded episodes during this time period.ResultsPatients had a mean age of 46 years and, contrasting with previous reports, nearly 50% of our patients did not have significant comorbidities. Ciprofloxacin resistance increased over the study period with 35% of isolates overall being resistant compared with only 3% exhibiting macrolide resistance. Despite a minority of patients receiving appropriate empirical antibiotic therapy, overall mortality was only 7%.ConclusionCampylobacter bacteremia remains a rare but significant cause of morbidity with a low associated mortality. Underlying immunosuppressive conditions are common but by no means universal. In our setting, macrolides would be favored as empirical agents to treat suspected Campylobacter enteritis, including cases with associated bacteremia.