کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5716636 | 1411161 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Carcinoma gástrico con estroma linfoide: 3 entidades clÃnico-patológicas
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
آسیبشناسی و فناوری پزشکی
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چکیده انگلیسی
Gastric carcinomas with lymphoid stroma comprise a heterogeneous group of incompletely characterized neoplasms that have not as yet been classified as different clinico-pathological entities. We analysed 13 cases of gastric carcinoma with lymphoid stroma in order to establish diagnostic criteria for their identification. We defined 3 different subtypes (patterns 1, 2 and 3) based on histopathologic, immunophenotypic and molecular criteria. Immunohistochemistry was performed to identify lymphoid populations (CD 3, CD4, CD8 and CD20), the presence of Epstein-Barr Virus (EBV) and the expression of DNA mismatch repair proteins. Our aim is to define criteria that are helpful in the differential diagnosis of these unusual lesions and to clarify the immunophenotype of their lymphoid population.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Española de PatologÃa - Volume 50, Issue 3, JulyâSeptember 2017, Pages 167-173
Journal: Revista Española de PatologÃa - Volume 50, Issue 3, JulyâSeptember 2017, Pages 167-173
نویسندگان
Álvaro Gutiérrez-Domingo, Carolina Manzotti, Katherine M. Gallardo-RodrÃguez, Adrián P. RodrÃguez-Caulo, Juan L. Gutiérrez-Cierco, Ignacio Gutiérrez-Domingo, José L. Villar-RodrÃguez,