کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
571873 | 1452605 | 2015 | 6 صفحه PDF | دانلود رایگان |

• First demonstration of field stability of EPA and DHA trait in transgenic plants.
• Most complex engineered plant trait to undergo field trialling to date.
• Demonstration of the feasibility of using agriculture to make fish oils.
The global consumption of fish oils currently exceeds one million tonnes, with the natural de novo source of these important fatty acids forming the base of marine foodwebs. Here we describe the first field-based evaluation of a terrestrial source of these essential nutrients, synthesised in the seeds of transgenic Camelina sativa plants via the heterologous reconstitution of the omega-3 long chain polyunsaturated fatty acid biosynthetic pathway. Our data demonstrate the robust nature of this novel trait, and the feasibility of making fish oils in genetically modified crops. Moreover, to our knowledge, this is the most complex example of plant genetic engineering to undergo environmental release and field evaluation.
Journal: Metabolic Engineering Communications - Volume 2, December 2015, Pages 93–98