کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5722263 1608116 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research paperLongitudinal monitoring of heartbeat dynamics predicts mood changes in bipolar patients: A pilot study
ترجمه فارسی عنوان
نظارت طولی بر پویایی ضربان قلب، تغییرات خلقی در بیماران دو قطبی را پیش بینی می کند: یک مطالعه آزمایشی
کلمات کلیدی
اختلالات دوقطبی، تنش قلبی، روانپزشکی، روانپزشکی بیولوژیک، ماشین بردار پشتیبانی شده،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی


- Heart Rate Variability was linked to somatic and mood disorders.
- We used supported vector machine (SVM) to classify mood states in bipolar disorder.
- SVM performed better if previous and subsequent mood states (MS) were considered.
- MS are not independent from each other but connected on a continuum.
- Evaluation of psychophysiological continuum may be relevant in clinical management.

ObjectivesRecent research indicates that Heart Rate Variability (HRV) is affected in Bipolar Disorders (BD) patients. To determine whether such alterations are a mere expression of the current mood state or rather contain longitudinal information on BD course, we examined the potential influence of states adjacent in time upon HRV features measured in a target mood state.MethodsLongitudinal evaluation of HRV was obtained in eight BD patients by using a wearable monitoring system developed within the PSYCHE project. We extracted time-domain, frequency-domain and non-linear HRV-features and trained a Support Vector Machine (SVM) to classify HRV-features according to mood state. To evaluate the influence of adjacent mood states, we trained SVM with different HRV-feature sets: 1) belonging to each mood state considered alone; 2) belonging to each mood state and normalized using information from the preceding mood state; 3) belonging to each mood state and normalized using information from the preceding and subsequent mood states; 4) belonging to each mood state and normalized using information from two randomly chosen states.ResultsSVM classification accuracy within a target state was significantly greater when HRV-features from the previous and subsequent mood states were considered.ConclusionsAlthough preliminary and in need of replications our results suggest for the first time that psychophysiological states in BD contain information related to the subsequent ones. Such characteristic may be used to improve clinical management and to develop algorithms to predict clinical course and mood switches in individual patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volume 209, February 2017, Pages 30-38
نویسندگان
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