کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5723536 1411455 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cholesterol Levels in Patients with Chronic Lymphocytic Leukemia
ترجمه فارسی عنوان
سطح کلسترول در بیماران مبتلا به لوسمی لنفوسیتی مزمن
کلمات کلیدی
پروفایل لیپید خون، سطح کلسترول، لوسمی لنفوسیتیک مزمن،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
چکیده انگلیسی
Low cholesterol levels may be accompanied by solid tumors or hematological malignancies such as multiple myeloma. Decreased cholesterol levels have been reported in some experimental studies about chronic lymphocytic leukemia (CLL). It may be associated with tumoral cell metabolism. Herein, we examine blood lipid profiles of patients with newly diagnosed CLL (284 male, 276 female, mean age 64 ± 11 years) as defined by National Cancer Institute criteria. The control group consisted of 71 healthy subjects with mean age 55 ± 9 years (28 male, 43 females). 60% of patients with Binet A, while 25% were Binet C. Decreased levels of total cholesterol, high density lipoprotein (HDL) and low density lipoprotein (LDL) were observed in patients with CLL than control group (p < 0,001). There was no statistical significance between CLL and control group for triglycerides (TG) and very low density lipoprotein (VLDL), also between HDL-C, VLDL, TG and grades. Cholesterol may metabolized by abnormal lymphocytes in CLL patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the National Medical Association - Volume 109, Issue 1, Spring 2017, Pages 23-27
نویسندگان
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