کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5731213 | 1611466 | 2017 | 5 صفحه PDF | دانلود رایگان |
BackgroundWe hypothesized that packed red blood cell (PRBC) transfusions from older donors would be associated with fewer nosocomial infections among trauma patients.MethodsWe performed a four-year retrospective analysis of 264 consecutive adult trauma patients who received â¥1 PRBC transfusion during admission. The capacity of donor age to predict nosocomial infection was assessed by logistic regression.ResultsThirty-three percent of all patients developed a nosocomial infection. Donor age was significantly higher among patients with nosocomial infection (40.3 vs. 37.6 years, p = 0.035), and the incidence of infection was directly proportional to donor age. The association between donor age and infection was strongest among recipients age â¥60 years, and was significant on multivariate regression for this cohort (OR 1.07 (95% CI 1.01-1.13), p = 0.024).ConclusionsAmong trauma patients receiving PRBC transfusions, blood from older donors may be associated with increased risk for nosocomial infection.
Journal: The American Journal of Surgery - Volume 214, Issue 4, October 2017, Pages 672-676