کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5731701 1611930 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewEffect of gum chewing on ameliorating ileus following colorectal surgery: A meta-analysis of 18 randomized controlled trials
ترجمه فارسی عنوان
بررسی تأثیر آدامس جویدن در بهبودی هیپوگلیسمی پس از عمل جراحی کولورکتال: متاآنالیز 18 آزمایش تصادفی
کلمات کلیدی
آدامس جویدن، ایلئوس، جراحی کولورکتال، متاآنالیز،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی


- A meta-analysis about gum chewing helps to ameliorate ileus following colorectal surgery was conducted.
- Chewing gum shewed to be an effective an secure solution to ileus following colorectal resection.
- ERAS programme and laparoscopic technique tended to negate the benefits of chewing gum.
- Sugared gum seemed to be less effective in ameliorating ileus following colorectal resection.

Background and objectiveChewing gum, as an alternative to sham feeding, had been shown to hasten the recovery of gut function following abdominal surgery. However, conclusions remained contradictory. We sought to conduct an updated meta-analysis to evaluate the efficacy of gum chewing in alleviating ileus following colorectal surgery.MethodsWe searched PubMed, EMBASE, and Cochrane Library Databases through February 2017 to identify randomized controlled trials (RCTs) evaluating the efficacy of the additional use of chewing gum following colorectal surgery. After screening for inclusion, data extraction, and quality assessment, meta-analysis was conducted by the Review Manager 5.3 software. The outcomes of interest were the time to first flatus, time to first bowel movement, length of hospital stay, and some clinically relevant parameters. We also performed subgroup analyses according to the type of surgical approaches or on trials that adopted enhanced recovery after surgery (ERAS) protocol or sugared gum.ResultsA total of 18 RCTs, involving 1736 patients, were included. Compared with standardized postoperative care, Chewing gum resulted in a shorter passage to first flatus [WMD = −8.81, 95%CI: (−13.45, −4.17), P = 0.0002], earlier recovery of bowel movement [WMD = −16.43, 95%CI: (−22.68, −10.19), P < 0.00001], and a reduction in length of hospital stay [WMD = −0.89, 95%CI: (−1.72, −0.07), P = 0.03]. Chewing gum was also associated with a lower risk of postoperative ileus [OR = 0.41, 95%CI: (0.23, 0.73), P = 0.003]. No evidence of significant advantages in overall postoperative complication, nausea, vomiting, bloating, readmission and reoperation towards the addition of chewing gum was observed. Subgroup analyses all favored gum chewing. However, the findings are hampered by the significant heterogeneity between trials.ConclusionsBased on current evidence, chewing gum offers an inexpensive, well-tolerated, safe and effective method to ameliorate ileus following colorectal surgery. However, tightly controlled, randomized and considerably larger multicenter trials are warranted to further validate our findings.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Surgery - Volume 47, November 2017, Pages 107-115
نویسندگان
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