کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5761709 | 1624801 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Trypanocide, antileishmania and cytotoxic activities of the essential oil from Rosmarinus officinalis L in vitro
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم زراعت و اصلاح نباتات
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چکیده انگلیسی
Rosmarinus officinalis L., like rosemary, is native to the Mediterranean and Asia and is one of the most popular culinary herbs cultivated around the world. It has been used to preserve food or improve its taste, such as in tea and in the preparation herb oils, butters and vinegars. The present study aimed to verify the leishmanicidal and trypanocidal potential of Rosmarinus officinalis L., as well as its essential oil cytotoxicity, in vitro. R. officinalis Lamiaceae presented α-pynene (10.71%), Camphor (11.81%), 1, 8 Cienole (32.90%) and β-caryophyllene (17.77%) as its major compounds. The essential oil's cytotoxic activity was present in low concentrations such as in those: 125 μg/mL and 62.5 μg/mL. Anti-trypanosome and anti-promastigote activity were respectively Ë125 μg/mL and Ë62.5 μg/mL, thus being considered clinically relevant. It is therefore concluded that the R. officinalis essential oil presents a compound with remarkable antiparasitic activity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Industrial Crops and Products - Volume 109, 15 December 2017, Pages 724-729
Journal: Industrial Crops and Products - Volume 109, 15 December 2017, Pages 724-729
نویسندگان
Pedro S. Pereira, Ana J. Maia, Saulo R. Tintino, CÃcera Datiane de M. Oliveira-Tintino, Iranir Sâmya de S. Raulino, Maria C. Vega, Miriam Rolón, Cathia Coronel, Luiz Marivando Barros, Antônia Eliene Duarte, Irwin R.A. de Menezes,