کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5761754 | 1624801 | 2017 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antioxidant and anticancer potential of bioactive compounds following UV-C light-induced plant cambium meristematic cell cultures
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم زراعت و اصلاح نباتات
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Antioxidant and anticancer potential of bioactive compounds following UV-C light-induced plant cambium meristematic cell cultures Antioxidant and anticancer potential of bioactive compounds following UV-C light-induced plant cambium meristematic cell cultures](/preview/png/5761754.png)
چکیده انگلیسی
Catharanthus roseus (L.) G. Don is a well-known medicinal plant as a potent anticancer agent that produces rich of secondary metabolites, such as phytochemicals, terpenoid indole alkaloids (TIAs) including catharanthine, vinblastine, vincristine, vindoline. In the present study illustrates the changes in phenolic contents, TIA contents and their biosynthesis pathway with High Performance Liquid Chromatography (HPLC) and quantitative reverse-transcription polymerase chain reaction qRT-PCR, and investigation of antioxidant and anticancer potential with their correlation by different Ultraviolet-C (UV-C) treated the condition in cambium meristematic cells (CMCs) from C. roseus. The UV-C was found to process high antioxidant capacity and anticancer potential. Moreover, the UV-C treatment enhanced accumulation of bioactive compounds such as total flavonoids, total phenolic, and TIAs, and also found a correlation with upregulation of TIA biosynthesis pathway genes. These results indicate that the UV-C treated C. roseus CMCs is a potential candidate to be used as natural antioxidant, anticancer agent and treatments of UV-C can be used as an efficient method to enhance bioactive compounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Industrial Crops and Products - Volume 109, 15 December 2017, Pages 762-772
Journal: Industrial Crops and Products - Volume 109, 15 December 2017, Pages 762-772
نویسندگان
So Hyun Moon, Bhupendra Mistry, Doo Hwan Kim, Muthuraman Pandurangan,