کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
577275 | 1453102 | 2013 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mechanisms of response to silver nanoparticles on Enchytraeus albidus (Oligochaeta): Survival, reproduction and gene expression profile
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بهداشت و امنیت شیمی
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چکیده انگلیسی
Silver has antimicrobial properties and silver nanoparticles (Ag-NPs) have been some of the most widely used NPs. Information regarding their effects is still insufficient, in particular for soil dwelling organisms. The standard soil Oligochaete Enchytraeus albidus was used to study the effects of Ag in soils, using differential gene expression (microarray) and population (survival, reproduction) response to Ag-NPs (PVP coated) and AgNO3. Results showed higher toxicity of AgNO3 (EC50Â <Â 50Â mg/kg) compared to toxicity of Ag-NPs (EC50Â =Â 225Â mg/kg). Based on the biological and material identity, the difference in toxicity between Ag-NPs and AgNO3 could possibly be explained by a release of Ag+ ions from the particles or by a slower uptake of Ag-NPs. The indications were that the responses to Ag-NPs reflect an effect of Ag ions and Ag-NPs given the extent of similar/dissimilar genes activated. The particles characterization supports this deduction as there were limited free ions measured in soil extracts, maybe related to little oxidation and/or complexation in the soil matrix. The possibility that gene differences were due to different levels of biological impact (i.e. physiological responses) should not be excluded. Testing of Ag-NPs seem to require longer exposure period to be comparable in terms of effect/risk assessment with other chemicals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Hazardous Materials - Volumes 254â255, 15 June 2013, Pages 336-344
Journal: Journal of Hazardous Materials - Volumes 254â255, 15 June 2013, Pages 336-344
نویسندگان
Susana I.L. Gomes, Amadeu M.V.M. Soares, Janeck J. Scott-Fordsmand, Mónica J.B. Amorim,