Degradation of high concentration 2,4-dichlorophenol by simultaneous photocatalytic-enzymatic process using TiO2/UV and laccase

► Coupling of native laccase with TiO2/UV decreased the 2,4-DCP degradation rate. ► TiO2/UV induced rapid inactivation of laccase. ► Immobilizing laccase to controlled porous glass significantly enhanced the stability of enzyme. ► Coupling of immobilized laccase with TiO2/UV increased the degradation of 2,4-DCP. ► Thermometric biosensor based on immobilized laccase detected 2,4-DCP precisely.