کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
579475 | 1453141 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Health risk characterisation for environmental pollutants with a new concept of overall risk probability
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بهداشت و امنیت شیمی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
In health risk assessment, risk is commonly characterised by calculating a simple hazard quotient (HQ), which cannot reflect the actual distribution of exposure and health effect values. This study aimed to develop a new risk characterisation method, the overall risk probability (ORP) method based on probabilistic techniques. Exposure exceedence values were calculated to obtain an exposure exceedence curve (EEC). The area under the EEC was calculated as the ORP value to represent the risk. This method was demonstrated by a case study for two steroidal EDCs, 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) for fish in surface water. It was found that the risk probability of fish exposed to E2 (ORP, 8.1%) and EE2 (ORP, 27%) were both above the reference value of 2.5%, which was consistent with the results of HQ method. Assuming independent action of individual EDCs, a combined risk probability of 33% was obtained for the mixture effects of E2 and EE2. Our results implicated that the adverse health effects imposed by E2 and EE2 were significant for fish in surface water worldwide.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Hazardous Materials - Volume 187, Issues 1â3, 15 March 2011, Pages 480-487
Journal: Journal of Hazardous Materials - Volume 187, Issues 1â3, 15 March 2011, Pages 480-487
نویسندگان
Qiming Cao, Qiming Yu, Des W. Connell,