کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5802370 | 1555666 | 2015 | 5 صفحه PDF | دانلود رایگان |

- First report of LC 50 of thymol, carvacrol and (E)-cinnamaldehyde for Amblyomma sculptum.
- First report of LC 50 of thymol, carvacrol and (E)-cinnamaldehyde for Dermacentor nitens.
- First report of synergism of thymol and carvacrol on A. sculptum.
- First report of synergism of thymol and carvacrol on D. nitens.
This study aimed at assessing the combined effect of thymol, carvacrol and (E)-cinnamaldehyde on Amblyomma sculptum and Dermacentor nitens larvae. The effects resulting from treatments were evaluated by means of the modified larval packet test. In order to determine the LC50, components of essential oils, the monoterpenes thymol, carvacrol and phenylpropanoid (E)-cinnamaldehyde were individually tested at different concentrations. After determining the LC50, each essential oil component was separately evaluated and then combined with another substance at a 1:1 proportion at the LC50 concentration and at 1/2 and 1/4 of the LC50. For A. sculptum, the lowest LC50 value was obtained for (E)-cinnamaldehyde (1.40Â mg/ml), followed by thymol (2.04Â mg/ml) and carvacrol (3.49Â mg/ml). The same order of effectiveness was observed for D. nitens, with values of 1.68, 2.17 and 3.33Â mg/ml, respectively. In the evaluation of component associations of essential oils against A. sculptum larvae, only the combinations between carvacrol and thymol (LC50) and carvacrol and (E)-cinnamaldehyde (1/4 LC50) presented a moderate synergetic effect. In turn, for D. nitens larvae, the combinations between thymol and carvacrol (LC50 and 1/2 LC50) presented a synergetic effect, while the others presented an additive or antagonistic effect. Therefore, it can be concluded that the combination of thymol and carvacrol (LC50) has a moderate synergetic effect against A. sculptum larvae, while thymol, combined with carvacrol (LC50 and 1/2 LC50), has a synergetic effect against D. nitens larvae.
Combinations that showed the best synergistic effect of association between thymol, carvacrol and (E)-cinamaldehyde on larvae of Amblyomma sculptum and Dermacentor nitens.99
Journal: Veterinary Parasitology - Volume 212, Issues 3â4, 15 September 2015, Pages 331-335