کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5806443 1555779 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Absence of correlation between karyotype profiles of Trypanosoma congolense and resistance to isometamidium chloride
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Absence of correlation between karyotype profiles of Trypanosoma congolense and resistance to isometamidium chloride
چکیده انگلیسی

Chromosome profiles of 10 Trypanosoma (T.) congolense populations with different isometamidium sensitivities were compared using the pulsed field gel electrophoresis technique. The aim was to elucidate whether there was a karyotype pattern specific to eight isometamidium resistant phenotypes. Analysis of the profiles indicated that all populations displayed several discrete bands at the region of small, intermediate and large chromosomes. The highest similarity was observed between two isolates originating from Burkina Faso, indicating that they had the same genetic origin. Other eight strains exhibited different patterns in terms of chromosome size and numbers such that there was no characteristic karyotype pattern that was established specifically to identify resistant populations and discriminate them from the sensitive ones. This study has revealed that isometamidium resistance is not correlated to karyotype profile in T. congolense.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Parasitology - Volume 147, Issues 3–4, 20 July 2007, Pages 311-314
نویسندگان
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