کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5810339 | 1114283 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Centaurea karduchorum Boiss. from Eastern Anatolia: Phenolic composition, antioxidant and enzyme inhibitory activities
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب مکمل و جایگزین
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Centaurea karduchorum Boiss. from Eastern Anatolia: Phenolic composition, antioxidant and enzyme inhibitory activities Centaurea karduchorum Boiss. from Eastern Anatolia: Phenolic composition, antioxidant and enzyme inhibitory activities](/preview/png/5810339.png)
چکیده انگلیسی
The phenolic composition of lyophilized hydrophilic extracts obtained from root, stem, leaf and flower of Centaurea karduchorum Boiss. a medicinal plant endemic to Eastern Anatolia (Turkey) used as anti-diabetic agent was characterized for the first time. Liquid chromatography mass spectrometry (LC/MS) analysis revealed that luteolin derivatives and chlorogenic acid were the dominating compounds contributing, respectively, from 16.1% (root) to 33.7% (stem) and from 7.3% (flower) to 12.0% (root) of total phenolics. Total reducing capacities of the extracts varied from 24.1 (root) to 38.5 (flower) mg gallic acid Eq./g DW [Folin-Ciocalteu assay] and from 274.0 (root) to 441.0 (stem) μmol Fe2+/g DW [FRAP assay]. The oxygen radical absorbance capacity (ORAC assay) values varied from 930.5 (root) to 1853.5 (stem) μmol trolox Eq./g DW. The leaf extract exhibited a pronounced inhibitory activity towards α-glucosidase (IC50: 0.63 ± 0.00 mg/ml) and a weak inhibitory activity towards amylase (IC50: 14.63 ± 0.67 mg/ml), which suggests a potential to reduce postprandial hyperglycaemia and supports its traditional use as antidiabetic agent.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Herbal Medicine - Volume 5, Issue 4, December 2015, Pages 211-216
Journal: Journal of Herbal Medicine - Volume 5, Issue 4, December 2015, Pages 211-216
نویسندگان
Abdullah Dalar, Yusuf Uzun, Muzaffer Mukemre, Musa Turker, Izabela Konczak,