کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5814723 1556643 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The two faces of the pharmacological interaction of mGlu2 and 5-HT2A - Relevance of receptor heterocomplexes and interaction through functional brain pathways
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
The two faces of the pharmacological interaction of mGlu2 and 5-HT2A - Relevance of receptor heterocomplexes and interaction through functional brain pathways
چکیده انگلیسی
► Broad evidence for a functional interaction in the brain of 5-HT2A and mGlu2 exists. ► The heteromerization of 5-HT2A-mGlu2 is discussed to directly account for these findings. ►Interaction of independent receptors could explain the functional cross-talk. ► A balanced review of the relevance of 5-HT2A-mGlu2 heteromers is provided. ►Questions about the existence of the putative heteromers could be addressed by new studies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropharmacology - Volume 70, July 2013, Pages 296-305
نویسندگان
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