The potential of nicotinic enhancement of cognitive remediation training in schizophrenia

► Drug treatments of cognitive deficits in schizophrenia have had limited success. ► Cognitive remediation training approaches involve considerable time requirements. ► Nicotinic agonists can facilitate sensory processing, attention, learning and memory. ► Effects constitute an ideal effects profile for enhancing training benefits. ► Coupling cognitive training with nicotinic agonists may accelerate training effects.