Egis-11150: A candidate antipsychotic compound with procognitive efficacy in rodents

► Egis-11150 is a candidate antipsychotic effective in preclinical psychosis models. ► Egis-11150 shows robust procognitive potency in four different animal models. ► Inhibitor of adrenergic alpha1, alpha2c, 5-HT2a, 5HT7 receptors with high affinity. ► Relatively selective blocker of adrenergic alpha2c over adrenergic alpha2a receptors.