Gestational and postpartum corticosterone exposure to the dam affects behavioral and endocrine outcome of the offspring in a sexually-dimorphic manner

► High maternal CORT antepartum increases depressive-like behavior in the offspring. ► High maternal CORT postpartum increases anxiety-like behavior in male offspring. ► Maternal CORT reprograms the offspring's HPA axis. ► Males and females are differently affected by exposure to elevated maternal CORT.