Rats tested after a washout period from sub-chronic PCP administration exhibited impaired performance in the 5-Choice Continuous Performance Test (5C-CPT) when the attentional load was increased

► Sub-chronic PCP treatment had no impact on the ability to conduct the 5C-CPT under baseline conditions following a 7-day washout period. ► Following an increase in the attentional load, animals sub-chronically treated with PCP exhibited an attentional impairment in the drug-free state. ► Sub-chronic PCP treatment induced a baseline-dependent attentional impairment in rats.