کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5817031 | 1116184 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Short communicationAntifungal and cytotoxic activities of the secondary metabolites from endophytic fungus Massrison sp.
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوشیمی بالینی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Short communicationAntifungal and cytotoxic activities of the secondary metabolites from endophytic fungus Massrison sp. Short communicationAntifungal and cytotoxic activities of the secondary metabolites from endophytic fungus Massrison sp.](/preview/png/5817031.png)
چکیده انگلیسی
Three novel compounds with spiro-5, 6-lactone ring skeleton has been isolated from the fermentation broth of Massrison sp. which could be isolated repeatedly from wild Rehmannia glutinosa. Psetariae oryza P-2b was applied to guide fractionation of bioactive compounds produced by Massrison sp. The molecular structures were established by a variety of one- and two-dimensional NMR experiments and the compounds with similar skeleton were reported for the first time from endophytic fungi of terraneous plant. Antifungal and cytotoxic activities of the compounds were tested, compounds 2 and 3 displayed stronger antifungal and cytotoxic activities. The compounds have the potential to be antibiotic against fungal pathogens and tumor cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytomedicine - Volume 18, Issue 10, 15 July 2011, Pages 859-862
Journal: Phytomedicine - Volume 18, Issue 10, 15 July 2011, Pages 859-862
نویسندگان
Zhen-Liang Sun, Ming Zhang, Ji-Fa Zhang, Jing Feng,