Altered gene expression profiles associated with enhanced skin inflammation induced by 12-O-tetradecanoylphorbol-13-acetate in streptozotocin-diabetic mice

► We produced a simple diabetes-enhanced inflammation model in mice. ► Diabetes variously modified cytokine mRNA expression at inflamed sites. ► Diabetes suppressed the reduction in mRNA levels of TNF-alpha and IL-1beta. ► TTP was not directly involved in the mRNA stabilization of TNF-alpha and IL-1beta.