TLRs, macrophages, and NK cells: Our understandings of their functions in uterus and ovary

► Interactions between immune system and female reproductive system play important roles in female fertility and reproductive health. ► Many normal events of female reproduction system can be considered as inflammatory process. ► Three components of immune systems, TLRs, macrophages and NK cells, are critical not only to provide protection against infections but also to modulate essential functions of uterus and ovary.