Stereocalpin A inhibits the expression of adhesion molecules in activated vascular smooth muscle cells

► Stereocalpin A is a chemical compound derived from the Antarctic lichen Stereocaulon alpium. ► Stereocalpin A inhibited VCAM-1 and ICAM-1expression. ► Inhibitory effect of stereocalpin A is mediated by the suppression of MAPK, Akt and NF-kB pathways.