In vitro bactericidal activity of diterpenoids isolated from Aframomum melegueta K.Schum against strains of Escherichia coli, Listeria monocytogenes and Staphylococcus aureus

Picture of Aframomum melegueta K.Schum (grains of paradise) with flowers and the structure of diterpene nucleus from which the bioactive compounds isolated from A. melegueata were derived. Modifications at R resulted in compounds with varying levels of bactericidal activity.208